Non-Homologous End Joining

Non-Homologous End Joining (NHEJ) is a natural DNA repair mechanism. It can introduce small insertions, deletions, or substitutions at the site of the DNA break. This often results in gene disruptions or mutations. Unlike HDR, NHEJ is not dependent on a homologous DNA sequence as a template.

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This entry was provided by the doctoral students of the GetRADI collaborative network. GetRADI is funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

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Non-Homologous End Joining