Chimeric Antigen Receptor (CAR) is a designed receptor (a protein which detects a signal) used in immunotherapy, particularly in the field of gene therapy. CAR is a synthetic receptor that combines components from different proteins. It is able to recognize a specific antigen on the surface of target cells, often cancer cells. After introducing the CAR inside the cell employing a gene vector, the CAR-bearing cells, such as hematopoietic stem cells or immune cells, can more effectively and specifically identify and attack cells displaying the targeted antigens to initiate a precise response against the disease.
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