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Adeno-associated virus (AAV)

Adeno-associated viruses (AAV)s are a group of non-disease-causing viruses. The group consists of nine different AAV subgroups, or serotypes, that can enter into different tissue types. AAVs genome is small, and composed of single-stranded DNA. In gene therapy, scientists can modify AAVs or the AAV genome to carry a helpful theraputic gene to patient cells. The modified AAVs carrying the helpful gene are known as recombinant AAV (rAAV) vectors.


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This entry was provided by the doctoral students of the GetRADI collaborative network. GetRADI is funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

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