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Cancer is a group of diseases characterised by the uncontrolled multiplication of a particular cell type. Scientists believe that understanding how stem cells self-renew indefinitely could help understand what goes wrong in cancer, and also use stem cell models to investigate how particular cancers progress. Many blood cancers are treated using a form of cell therapy (haematopoietic stem cell transplant, or bone marrow transplant). Certain blood cancers can currently be treated using combined gene and cell therapy (CAR-T therapy), and researcher are investigating whether this therapy might be used to treat other cancers, including solid tumours. In this section you will find factsheets about different cancers, existing gene and cell-based therapies, and ongoing research in this area, as well as guidelines as to where you can look for support if you or a loved one are living with cancer.